I had the same problem today.
I updated to iOS10 yesterday.
Exactly the same set up as you (iPad mini 2 etc).
Flew today and sometimes it went 30 minutes before disconnecting from the Garmin Glo GPS, sometimes only a few minutes.
In two flights of 1.5 hours each, it must have disconnected about ten times. Had to turn off the Garmin Glo, turn it on again and re-connect.
Very annoying!

Also emailed Garmin regarding this and received the following response....

Hello,

Unfortunately, there is a problem with the iOS 10 update that is causing the GLO to to stop receiving your GPS location. Our development team is working on a fix that should be available soon. We apologize for this inconvenience.


Best Regards,

Can you confirm that the issue went away after you downgraded to 9.3.5 again?

I have the same problem, iPad Mini 2, GLO 2.80, and iOS 10.1 Beta.
Currently back to iOS 9.3.5

Some additional information: it looks like if you switch to another GPS enabled application on the iPad when Skydemon is in the status Waiting for Location data that the other application is able to acquire location data without a problem.

Ever since upgrading to iOS 10 I have issues losing my location data (Waiting for Location Data) in Skydemon during flights, sometimes it works for a couple of minutes but not stable anymore like with iOS 9.x.
I am in contact with at least 4 other members of our flying club wo are experiencing the same behaviour. It’s really strange, sometimes having location data for e.g. 30 minutes but sometimes you are not able to keep location data for 5 seconds. Of course during the whole time the GLO keeps fix and the bluetooth connection stays active!

The equipment we are using is:
- iPad mini (2) with iOS 10.0.2
- Garmin GLO with with latest firmware 2.80 (also 2.70 was tested)
- Skydemon version 3.6.5.51

Extra info, one of the other guys already downgraded his iOS back to latest iOS 9 to see if stability returns.

Any other people having the same stability issues?

Regards

Rob